Selected publications

2023

Mollereau B, Hayflick, Issa AR, et al. A burning question from the first international BPAN symposium: is restoration of autophagy a promising therapeutic strategy for BPAN? Autophagy (2023);19(12):3234-3239.

2022

Issa AR*, Menzies JAC , Padmanabhan A and Alonso C.R*. A novel post-developmental role of the Hox genes underlies normal adult behaviour. PNAS (2022) ;119(49):e2209531119. (*) co-corresponding.

2021

Dulac A., Issa AR, Sun J., Matassi G., Chérif-Zahar B., Cattaert D., Birman S. A novel and specific regulator of neuronal V-ATPase in Drosophila. eNeuro (2021). ENEURO.0193-21.

Klann M., Issa AR, and Alonso C.R. microRNA-dependent control of sensory neuron function regulates posture behaviour in Drosophila. J. Neurosci (2021) ; 10.1523/JNEUROSCI.0081-21.2021.

2019

Issa AR.*, Picao-Osorio J.*, Rito N., Chiappe M.E. and Alonso C.R. A Single microRNA-Hox gene module controls equivalent movements in biomechanically distinct forms of Drosophila. Curr. Biol. (2019) ; 29(16), 2665-2675.e4. (*) Equal contribution.

Robin M., Issa AR, Birman S. and Mollereau B. Drosophila p53 integrates the antagonism between autophagy and apoptosis in response to stress. Autophagy (2019) ; 15(5):771-784.

2018

Issa AR, Sun J., Petitgas C., Mesquita A., Dulac A., Jenny A., Chérif-Zahar B., and Birman S. The lysosomal membrane protein LAMP-2A promotes autophagosome formation and prevents Parkinson’s disease-like symptoms in the Drosophila brain. Autophagy (2018) ;14(11):1898-1910.

2017

Vaccaro A., Issa AR, Seugnet L., Birman S. and Klarsfeld A. Locomotor Aging in a Drosophila Clock Mutant Links Circadian and Dopaminergic Neuron Subsets in the Central Brain. Plos Genetics (2017). 13(1):e1006507.

2015

Cassar* M., Issa AR*, Riemensperger T.*, Petitgas C., Rival T., Coulom H., Iché-Torres M., Han K.-A. and Birman S. A dopamine receptor contributes to paraquat-induced neurotoxicity in Drosophila. Hum Mol Genet.(2015) Jan 1 ;24(1):197-212.

2013

Riemensperger T, Issa AR*, Pech U.*,Coulom H, Nguyễn M-V, Cassar M., Jacquet M., Fiala A. and Birman S. A single dopamine pathway underlies progressive locomotor deficits in a Drosophila model of Parkinson disease. Cell Reports (2013), 5 :1–9. (*) Equal contribution.